Impact of Yoga on Immune Response with Special Reference to COVID- 19: A Review of Randomized Controlled Trials

Abstract

Abstract: Like other viruses, severe acute respiratory syndrome coronavirus-2 (SARS-CoV- 2) continuously evolves due to mutations during genome replication. These mutations lead to various new variants and may alter the pathogenicity, immune escape capacity, and re-infection risk. In addition, it is also evident that a compromised immune system increases the susceptibility and severity of the disease. Therefore, strengthening the immune system is considered to combat Covid. Yoga is an ancient practice used for strengthening the body and mind. There are abundant studies that focus on yoga's benefits for stress management; however, lesser studies observed the effects of yoga on the immune system. Therefore, the present study aims to compile randomized controlled studies on the role of yoga in immunity and COVID-19. Our finding reported moderate evidence for the benefits of yoga in the levels of inflammatory markers, such as C-reactive protein (CRP), and cytokines, such as interleukin (IL) and tumor necrosis factor-alpha (TNF-α). However, lesser shreds of evidence were observed on the effect of yoga on innate and adaptive immunity. Our finding reported a paucity of studies examining the impact of yoga on the immunity of Covid patients. Thus, its efficacy as a potential adjuvant to attenuate Covid-19 infection has yet to be proven. Further extensive studies are recommended to draw the inference on the impact of yoga on COVID-19.