Affiliation:
1. Guru Gobind Singh College of Pharmacy, Yamuna Nagar 135001, Haryana, India
Abstract
Background::
A Liposomal delivery system is a novel and distinguishing way of organized
medicine administration. The advancements in liposomal technology allow for controlled
drug distribution to treat rheumatoid arthritis effectively. Liposomes are microscopic lipid-based
vesicles that have shown promise in transporting substances, such as superoxide dismutase, hemoglobin,
erythrocyte interleukin-2, gamma interferon, and smaller compounds.
Objective::
Liposomes are biocompatible, nontoxic, biodegradable, non-immunogenic, and flexible,
with sizes ranging from 0.025 to 2.5 micrometers. LDS is normally employed to distribute
drugs through topical conduits, but fresh investigation has shown that it offers promise for oral, ocular,
and parenteral administration. Our major objective is to gather information about liposomes,
focusing on their applicability in rheumatoid arthritis treatment.
Methods::
In the current review, we have tried to cover the preparation techniques, clinical trials,
patents, marketed formulations, vesicle types, formulations used to treat rheumatoid arthritis and
other ailments, and layered liposomal formulations with improved characteristics.
Conclusion::
Research has established LDS as a biocompatible, sustainable, non-toxic, adaptable
material. Researchers working on LDS technology in rheumatoid arthritis will find this review particularly
useful as it may unclutter novel ways for therapeutic intercessions in treating the disease.
Publisher
Bentham Science Publishers Ltd.