Affiliation:
1. Department of Pharmacy, Jagannath University, Bahadurgarh, Haryana, 124507, India
Abstract
Abstract:
Prediabetes increases the risk of type 2 diabetes, metabolic syndrome, chronic renal
disease, and cardiovascular disease in a person. In current practice, five alternative definitions of
prediabetes are utilized, each based on different HbA1C, fasting glucose, and 2-hour glucose cut
points. Prediabetes is a common condition that occurs between normal glycemia and diabetes. It
is more common in elderly and obese people. The prevalence of prediabetes and diabetes can be
influenced by a variety of individual, family, and societal variables. Additionally, as diabetes is
the primary contributor to non-communicable diseases (NCD), it is crucial to identify the key
temporal variables for diabetes early diagnosis. In turn, effective prediabetes and diabetes
awareness, control, and preventive programs may be created by policymakers and public health
professionals worldwide. Popular pathogenic pathways in prediabetes include insulin resistance,
inflammation, and sensitivity to insulin. HBA1C, OGTT, and FPG are discussed as the diagnostic
criteria in order of frequency. The most commonly researched therapies in the realm of prediabetes
are metformin, exercise, and physical activity. Physiological markers including
BMI, blood pressure, and waist circumference prompted relatively significant concern. Despite
declining trends, the study demonstrates that prediabetes and diabetes are widely prevalent. In
order to prevent non-communicable illnesses, the research suggests encouraging healthy lifestyles
and regular screenings.
Publisher
Bentham Science Publishers Ltd.