1. Cesmac University Center, Pharmacy Department, Maceió 57051-160, Brazil
2. Drug Development and Synthesis Laboratory, Department of Pharmacy, State University of Paraíba, Campina Grande 58429-500, Brazil
3. Post-graduate Program in Pharmaceutical Sciences, State University of Paraíba, Campina Grande 58429-500, Brazil
4. Post-graduate Program in Bioinformatics, Bioinformatics Multidisciplinary Environment, Federal University of Rio Grande do Norte, Natal, Brazil.
5. Post-graduate Program in Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Rio Grande do Norte, Natal, Brazil.