Affiliation:
1. Department of Pharmacy, Faculdade de Farmácia, Laboratório de Controle de Qualidade, Universidade Federal de
Goiás, Rua 240, s/n, Setor Leste Universitário, CEP 74605-170, Goiânia - GO, Brasil
Abstract
Introduction:
A new, ecological, and stability-indicating method by HPLC was developed for
the quantification of moxifloxacin in tablets. A C18 column at 33°C, purified water acidified with 0.2%
phosphoric acid and ethanol (74:26,v/v), flow rate at 1.0 mLmin-1
, injection volume of 5 µL, and detection at 290 nm was used.
Methods:
The method was linear (2-12 µgmL-1
), selective, accurate (100.86%), precise (RSD<2%), and
robust.
Results:
The retention time for moxifloxacin in tablets was approximately 4.4 minutes.
Conclusion:
To sum up, a method based on the principles of green analytical chemistry was successfully
developed and validated for the quantification of moxifloxacin in tablets
Publisher
Bentham Science Publishers Ltd.
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献