Eco-Friendly Methodologies for the Synthesis of Quinoline Nucleus-Reference-Cited by-同舟云学术

Eco-Friendly Methodologies for the Synthesis of Quinoline Nucleus

Published:2019-08-27 Issue:6 Volume:16 Page:602-608
ISSN:1570-193X
Container-title:Mini-Reviews in Organic Chemistry
language:en
Short-container-title:MROC

Author:

da Silveira Pinto Ligia S.¹,Vasconcelos Thatyana R. Alves¹,de Souza Marcus V.N.²

Affiliation:

1. Instituto de Quimica, Universidade Federal Fluminense, Rio de Janeiro, Brazil

2. Instituto de Tecnologia em Farmacos- Far Manguinhos, Fundacao Oswaldo Cruz, Rio de Janeiro, Brazil

Abstract

The quinoline nucleus is a very important class of heterocyclic aromatic compounds present in several drugs on the market, with synthetic methodologies being necessary to prepare its nucleus and derivatives. Considering that fact, the aim of this review is to describe the development of eco-friendly methodologies for the synthesis of quinoline nucleus and its derivatives in the last five years. Thus, throughout the text are presented varios reagents and catalysts used in the synthesis of quinoline nucleus, the reaction conditions, the advantages of the described methodologies, along with the reaction scheme and some reaction mechanisms.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry

Reference15 articles.

1. Marella A.; Tanwar O.P.; Saha R.; Ali M.R.; Srivastava S.; Akhter M.; Shaquiquzzaman M.; Alam M.M.; Quinoline: A versatile heterocyclic. Saudi Pharm J 2013,21,1-12

2. Bharate J.B.; Vishwakarma R.A.; Bharate S.B.; Metal-free domino one-pot protocols for quinoline synthesis. RSC Advances 2015,5,42020-42053

3. Barbosa-Lima G.; Da Silveira Pinto L.S.; Kaiser C.R.; Wardell J.L.; De Freitas C.S.; Vieira Y.R.; Marttorelli A.; Cerbino Neto J.; Bozza P.T.; Wardell S.M.S.V.; de Souza M.V.N.; Souza T.M.L.; N-(2-(arylmethylimino)ethyl)-7-chloroquinolin-4-amine derivatives, synthesized by thermal and ultrasonic means, are endowed with anti-Zika virus activity. Eur J Med Chem 2017,127,434-441

4. Barbosa-Lima G.; Moraes A.M.; Araújo A.D.S.; da Silva E.T.; de Freitas C.S.; Vieira Y.R.; Marttorelli A.; Neto J.C.; Bozza P.T.; de Souza M.V.N.; Souza T.M.L.; 2,8-bis(trifluoro-methyl) quinoline analogs show improved anti-Zika virus activity, compared to mefloquine. Eur J Med Chem 2017,127,334-340

5. Singh A.; Prakash V.; Kant S.; Kumar R.; Bhatia A.; Verma A.K.; Srivastava A.; Bedaquiline: A new hope in treatment of tuberculosis. Int J Health Allied Sci 2016,5(3),172-173

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