A Review on the Recent Multicomponent Synthesis of 4H-Pyran Derivatives

Author:

El-Bana Ghada G.1,Salem Mohammed A.2,Helal Mohamed H.3,Alharbi Osama4,Gouda Moustafa A.5

Affiliation:

1. Department of Chemistry, Faculty of Science, Mansoura University, El-Gomhoria Street, Mansoura 35516, Egypt | Laboratory Department, University Student Hospital, Mansoura University, El-Gomhoria Street, Mansoura ET- 35516, Egypt

2. Department of Chemistry, Faculty of Arts and Science, King Khalid University, Mohail Assir, KSA. | Department of Chemistry, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt

3. Department of Chemistry, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt | Department of Chemistry, Faculty of Arts and Science, Northern Border University, Rafha, KSA

4. Department of Chemistry, Faculty of Science and Arts, Ulla, Taibah University, KSA

5. Department of Chemistry, Faculty of Science, Mansoura University, El-Gomhoria Street, Mansoura 35516, Egypt | Department of Chemistry, Faculty of Science and Arts, Ulla, Taibah University, KSA

Abstract

Abstract: 4H-Pyran is a well-known moiety, which appears in various natural and synthetic products. These compounds include various biological activities like anti-hepatotoxic, antitumor, anti-inflammatory, antioxidant, anti-spasmolytic, diuretic, estrogenic, anticoagulant, antifungal, antiviral, anti-helminthic, antimicrobial, hypothermal, anti-tubercular, anti-HIV, herbicidal, anticonvulsant and analgesic activity. This review has summarized an overview of general strategies that allow the design of 4H-pyran derivatives via catalyzed one-pot multicomponent reactions.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry

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