Affiliation:
1. Department of Chemistry, Banasthali Vidyapith, Banasthali, 304022, Rajasthan, India
2. Department of Chemistry & Division of
Research and Development, Lovely Professional University, Phagwara, 144411, Punjab, India
Abstract
Abstract:
1,4-benzodiazepines play a valuable role in organic and medicinal chemistry. In
this review article, we have mainly discussed the synthesis of various 1,4-benzodiazepines in
the presence of a palladium catalyst. Different reactions, such as intramolecular N-arylation,
reductive elimination, oxidative addition, intramolecular alkylation, C-H activation, aryl-aryl
bond formation, etc., are included. For these types of syntheses, an easy and efficient catalytic
domino process has been reported, including the intermolecular or intramolecular reactions. In
this review article, we have also discussed catalyst regeneration and some ligand-free Pdcatalyzed
reactions.
Publisher
Bentham Science Publishers Ltd.
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