Affiliation:
1. Department of Chemistry, Government College Women University, Faisalabad-38000, Pakistan
2. Department of Biochemistry, Sardar Bahadur Khan Women’s University, Quetta, Pakistan
Abstract
In our present work, we emphasized on the potential of barbituric acid (1) derivatives
as drugs like anti-bacterial, hypnotic, sedative, anti-microbial and antifungal
agents. As naturally occurring, barbituric acid (1) is inactive but in the derivative form, it
has a large number of medicinal uses and nowadays, it has a great demand in the pharmaceutical
industry. Barbituric acid has a wide range of applications in the synthesis of a diverse
class of compounds like heterocyclic, carbocyclic, synthetic alkaloids, and due to its
broad-spectrum applications, barbituric acid acquired the position of building blocks in
synthetic chemistry. Through the history of humanity, a number of bioactive agents have
been applied to cure the disease related to hypnotics and sedatives, while the exact efficacy
of these agents was found to be limited. Till now, review articles on barbituric acid
only express their specific aspect but in present review article, all aspects are discussed in detail to provide a
platform to readers and researchers so that they could obtain all information and background knowledge from a
single point.
Publisher
Bentham Science Publishers Ltd.
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