Affiliation:
1. Organic Chemistry Department, Faculty of Chemistry, Uzhhorod National University, Uzhhorod, Ukraine
Abstract
The investigation of effective and green synthetic routes to approach to novel fused
heterocycles with pyridopyrimidine and pyridopyrazine scaffolds stirs up broad interest from
scientists as they are capable of providing valuable properties such as anticancer and antimicrobial
activities and they are proved γ-secretase modulators, polymers, and corrosion inhibitors.
This causes a steady increase in the number of publications on titled condensed systems.
The present review article summarizes recent literature data from 2010 to 2020 on the
methods of synthesis, chemical transformations and biological properties of condensed
bicyclic systems of pyridopyrimidine and pyridopyrazine with a bridgehead nitrogen atom to
establish the current state of the art in this area.
Funder
Ministry of Education and Science of Ukraine
Publisher
Bentham Science Publishers Ltd.
Cited by
3 articles.
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