Bioactivities and Structure-Activity Relationships of Usnic Acid Derivatives: A Review-Reference-Cited by-同舟云学术

Bioactivities and Structure-Activity Relationships of Usnic Acid Derivatives: A Review

Published:2024-08 Issue:14 Volume:24 Page:1368-1384
ISSN:1389-5575
Container-title:Mini-Reviews in Medicinal Chemistry
language:en
Short-container-title:MRMC

Author:

Nie Wen-Zhe¹,Shen Qing-Kun¹,Quan Zhe-Shan¹,Guo Hong-Yan¹,Li Ya-Mei²

Affiliation:

1. Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, 133002, China

2. Department of Pharmacy, Shandong Second Provincial General Hospital, Jinan, Shandong, China

Abstract

Abstract: Usnic acid has a variety of biological activities, and has been widely studied in the fields of antibacterial, immune stimulation, antiviral, antifungal, anti-inflammatory and antiparasitic. Based on this, usnic acid is used as the lead compound for structural modification. In order to enhance the biological activity and solubility of usnic acid, scholars have carried out a large number of structural modifications, and found some usnic acid derivatives to be of more potential research value. In this paper, the structural modification, biological activity and structure-activity relationship of usnic acid were reviewed to provide reference for the development of usnic acid derivatives.

Funder

Higher Education Discipline Innovation Project

National Natural Science Foundation of China

Key Projects of Jilin Province Science and Technology Development Plan

Jilin Scientific and Technological Development Program

Education Department Project of Jilin

Publisher

Bentham Science Publishers Ltd.

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