Author:
Carta Mauro Giovanni,Pintus Elisa,Zaccheddu Rosanna,Callia Omar,Conti Giuliana,Aviles Gonzalez Cesar Ivan,Minerba Luigi,Demontis Roberto,Pau Massimiliano,Cocco Eleonora,Penna Maria Petronilla,Kalcev Goce,Lorrai Stefano,Velluzzi Fernanda,Lovoselli Andrea,Monticone Marco,Massidda Maria Valeria,Pinna Maria Rita,Atzori Laura,Cauli Alberto,Scano Alessandra,Orrù Germano,Crisafulli Antonio,Cosentino Sofia,Machado Sergio,Fortin Dario,Migliaccio Gian Mario,Finco Gabriele,Musu Mario,Cossu Giulia
Abstract
Introduction:
The purpose is to verify in old adults if social and behavioral rhythms (SBRs) are correlated with a positive perception of the quality of life (QoL). Social and behavioral rhythms and related circadian biorhythms are known as central points in the pathophysiology of bipolar disorders. A secondary aim is to see if a similar relationship can be found in Major Depressive Disorder (MDD) in old adults. Sample: 141 people aged ≥65 years (58.9% Female).
Methods:
Each subject was evaluated using the Social and Behavioral Rhythms Scale (in which higher scores show more dysfunctional SRBs); SF-12 for QoL and a screening tool for depressive symptoms. They underwent a medical evaluation and blood level assays including cholesterol and triglycerides. The medical diagnoses including MDD were taken into account.
Results:
The Social and Behavioral Rhythms Scale score correlated inversely with SF-12 score (p<0.001) and positively with PHQ9 (p<0.0001). People with MDD had a higher score on social rhythms than controls without (p<0.01). The study highlighted, for the first time, that social and behavioral rhythms have a role in old adults living in the community.
Conclusion:
Further longitudinal studies with a sufficient number of individuals will be required to confirm these data and clarify causal links of the association.
Publisher
Bentham Science Publishers Ltd.