Rebalancing the Oral Microbiota as an Efficient Tool in Endocrine, Metabolic and Immune Disorders

Author:

Isacco Ciro Gargiulo1ORCID,Ballini Andrea2ORCID,De Vito Danila3ORCID,Nguyen Kieu Cao Diem4ORCID,Cantore Stefania1ORCID,Bottalico Lucrezia5ORCID,Quagliuolo Lucio2ORCID,Boccellino Mariarosaria2ORCID,Di Domenico Marina2ORCID,Santacroce Luigi6ORCID,Arrigoni Roberto7ORCID,Dipalma Gianna1ORCID,Inchingolo Francesco1ORCID

Affiliation:

1. Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", 70121 Bari, Italy

2. Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80100 Naples, Italy

3. Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari "Aldo Moro", 70121 Bari, Italy

4. Human Stem Cell Research Center-HSC, Ho Chi Minh City, Vietnam

5. PolyPheno S.r.l. Academic Spin Off, University of Bari "Aldo Moro", 74123 Taranto, Italy

6. Jonian Department, University of Bari "Aldo Moro", 70121 Bari, Italy

7. CNR Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), 70125 Bari, Italy

Abstract

The current treatment and prevention procedures of oral disorders follow a very targeted approach considering mouth and its structures as a system that is completely independent, than the rest of the body. The main therapeutic approach is to keep the levels of oral bacteria and hygiene in an acceptable range compatible with oral-mouth health, completely separated from systemic microbial homeostasis (eubiosis vs dysbiosis). This can negatively impact the diagnosis of a more complex systemic disease and its progression. Dysbiosis occurs as a consequence of imbalance in oral and gut microbiota which leads to cardiovascular diseases, diabetes mellitus, rheumatoid arthritis, and Alzheimer’s disease, as reported in current literature. Likewise, there is a need to highlight and develop a novel philosophical approach in the treatments for oral diseases that will necessarily involve nonconventional approaches.

Publisher

Bentham Science Publishers Ltd.

Subject

Immunology and Allergy,Endocrinology, Diabetes and Metabolism

Cited by 45 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3