Evaluation of comedogenic potential of a moisturizer venusia max lotion (PAMA free)

Abstract

: Being commonly used skin care products, comedogenic potential of moisturizers should be assessed. : The aim of the study was to evaluate the comedogenic potential of a moisturizer Venusia Max Lotion (paraben-, alcohol-, mineral oil-, animal origin-(PAMA) free) when applied topically to the skin compared to the controls. : Double-blind, single-center, comparative study conducted at private institute in Mumbai, India: Approximately 0.025 gm of the test product and 0.025 ml of positive control (coconut oil) and negative control (glycerin) were applied and occluded under a patch on the upper back of healthy female participants. Patch application and removal were made 12 consecutive times on alternate days for each participant. On the last day, approximately 2 hours after patch removal, a follicular biopsy was taken for all participants on all product application zones. : Data analyzed with descriptive statistics using the SPSS software version 10.0.: Data from a total of 19 participants was analyzed. The mean age was 35.32 years. The mean comedone grade for Venusia Max Lotion (PAMA free) was significantly lower compared to the positive control (Coconut Oil) (1.00 vs. 2.11, respectively; P=.001). The mean comedone grade was 0.79 for negative control (Glycerine) which is nearly similar to that of the test product. The moisturizer product Venusia Max Lotion (PAMA free) is non-comedogenic as compared to positive control. Thus, it can be considered for moisturizing purposes without the fear of comedogenicity.