Clinical Features and Gaps in the Management of Probable Familial Hypercholesterolemia and Cardiovascular Disease

Author:

Zafrir Barak1,Jubran Ayman1,Lavie Gil2,Halon David A.1,Flugelman Moshe Y.1,Shapira Chen3

Affiliation:

1. Department of Cardiology, Lady Davis Carmel Medical Center

2. Department of Medicine, Lady Davis Carmel Medical Center

3. Clalit Health Services

Publisher

Japanese Circulation Society

Subject

Cardiology and Cardiovascular Medicine,General Medicine

Reference26 articles.

1. 1. Nordestgaard BG, Chapman MJ, Humphries SE, Ginsberg HN, Masana L, Descamps OS; European Atherosclerosis Society Consensus Panel. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: Guidance for clinicians to prevent coronary heart disease: Consensus statement of the European Atherosclerosis Society. Eur Heart J 2013; 34: 3478–3490.

2. 2. Goldberg AC, Hopkins PN, Toth PP, Ballantyne CM, Rader DJ, Robinson JG; National Lipid Association Expert Panel on Familial Hypercholesterolemia. Familial hypercholesterolemia: Screening, diagnosis and management of pediatric and adult patients: Clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Clin Lipidol 2011; 5(3 Suppl): S1–S8.

3. 3. Hovingh GK, Kastelein JJ. Diagnosis and management of individuals with heterozygous familial hypercholesterolemia: Too late and too little. Circulation 2016; 134: 710–712.

4. 4. Zafrir B, Jubran A, Lavie G, Halon DA, Flugelman MY, Shapira C. Clinical determinants and treatment gaps in familial hypercholesterolemia: Data from a multi-ethnic regional health service. Eur J Prev Cardiol 2017; 24: 867–875.

5. 5. Hopkins PN, Toth PP, Ballantyne CM, Rader DJ; National Lipid Association Expert Panel on Familial Hypercholesterolemia. Familial hypercholesterolemias: Prevalence, genetics, diagnosis and screening recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Clin Lipidol 2011; 5(3 Suppl): S9–S17.

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