THE INFLUENCE OF DENTAL GEL AND GLYCINE ON THE PSYCHOLOGICAL AND DENTAL STATUS OF CADETS OF THE DEPARTMENTAL INSTITUTE IN THE DISORDER OF ADAPTIVE REACTIONS

Abstract

Dental diseases are a frequent manifestation of disorders of adaptive reactions, since the negative impact on the immune status of cadets is reflected in changes in the microflora of the oral cavity and periodontal [2, 5, 7, 9]. The goal is to improve the therapeutic and preventive measures of inflammatory periodontal diseases caused by a disorder of adaptive reactions in cadets of the departmental institute. Matherials and methods. The group of the examined consisted of 171 people – cadets of 1–4 courses of the Ufa Law Institute of the Ministry of Internal Affairs of the Russian Federation in the Republic of Bashkortostan, aged 18–23 years. The study consisted of psychological testing, determination of the state of their vegetative reactions and cortisol content in saliva, molecular genetic determination of the composition of frequently occurring periodontopathogenic bacteria of the dentoalveolar furrow and enzyme immunoassay of the content of cytokines in the oral fluid of proinflammatory, cellular regulatory and immunosuppressive action. Results. The antimicrobial effect of the course application of supravival applications of dental gel Phagodent, together with Glycine, is manifested by a decrease in the frequency of detection of periodontal pathogenic bacteria - Tanerella forsythia and Aggregatibacter actinomycetemcomitans in persons with periodontal diseases not associated with a disorder of adaptive reactions. The use of supramural applications of dental gel is accompanied by a significant decrease in the level of IL-4, IL-12, IL-1ß, TFR-β in the oral fluid of persons with a disorder of adaptive reactions and periodontal inflammation. Conclusion. After the use of dental gel Phagodent and Glycine, there was a 4-fold decrease in the possibility of recurrence of periodontal diseases, the frequency of detection of Aggregatibacter actinomycetemcomitans in the microflora of the dental sulcus decreased by 66% of the frequency and Tannerella forsythia – by 30%, a decrease in the levels of IL-4, IL-12, IL-1ß, TFR-β in the oral fluid in the group with disorder of adaptive reactions and periodontal inflammation, as well as IL-10, TNF-α and IL-1β in the group without disorder, but with periodontal inflammation.