Extended study: experience of using rehabilitation magnetotherapy in patients with melanoma receiving immunotherapy

Author:

Koneva E. S.ORCID, ,Mochalova A. S.ORCID,Suetina M. S.ORCID, , ,

Abstract

Immunotherapy is becoming an increasingly popular cancer treatment method due to its high specificity and potential to be more effective than traditional approaches. The problem of the use of concomitant rehabilitation measures remains in the highlight, as they can help reduce unwanted side effects of the main treatment and improve the overall quality of life of patients. Purpose of the study. To expand the comparative analysis of the quality of life of patients diagnosed with melanoma and receiving immunotherapy, as well as the overall response rate during treatment with the use of accompanying rehabilitation magnetotherapy. Materials and methods. The study included 128 patients diagnosed with melanoma and receiving immunotherapy with pembrolizumab or nivolumab. The patients of the study group (n = 67) underwent a course of immunotherapy and an accompanying course of rehabilitation magnetotherapy. The patients in the control group underwent a course of immunotherapy without accompanying rehabilitation magnetotherapy. Treatment efficacy was assessed according to iRECIST 1.1 criteria. The EORTC QLQ-C30 questionnaire was used to study the quality of life. The degree of adverse events was assessed according to CTCAE 5.0 criteria. Results. The use of accompanying rehabilitation magnetotherapy during the course of immunotherapy led to an improvement in the overall quality of life of patients and a decrease in treatment side effects. Further research in this area is needed in order to determine the potential of magnetotherapy as an additional rehabilitation method.

Publisher

PANORAMA Publishing House

Subject

General Medicine

Reference16 articles.

1. 1. Okamura H. Importance of rehabilitation in cancer treatment and palliative medicine. Jpn J Clin Oncol. 2011 Jun; 41 (6): 733-8. doi: 10.1093/jjco/hyr061. PMID: 21622762.

2. Roles of UVA radiation and DNA damage responses in melanoma pathogenesis;Khan;Environ Mol Mutagen,2018

3. 3. https://www.wcrf.org/cancer-trends/skin-cancer-statistics/

4. 4. Kaprin A.D., Starinskii V.V., Shakhzadova A.O. Sostoianie onkologicheskoi pomoshchi naseleniiu Rossii v 2020 godu [The state of cancer care for the population of Russia in 2020]. Moscow Scientific Research Oncological Institute named after P.A. Herzen - branch of the Federal State Budgetary Institution «National Medical Research Center of Radiology» of the Ministry of Health of Russia, 2021. (In Russ.)

5. 5. Rager T, Eckburg A, Patel M, Qiu R, Gantiwala S, Dovalovsky K, et al. Treatment of Metastatic Melanoma with a Combination of Immunotherapies and Molecularly Targeted Therapies. Cancers (Basel). 2022; 14 (15).

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3