The insulinotropic effect of exogenous glucagon-like peptide-1 is not affected by acute vagotomy in anaesthetized pigs

Author:

Veedfald Simon1,Hansen Marie1,Christensen Louise Wulff1,Larsen Sara Agnete Hjort1,Hjøllund Karina Rahr1,Plamboeck Astrid1,Hartmann Bolette1,Deacon Carolyn Fiona1,Holst Jens Juul1

Affiliation:

1. Department of Biomedical Sciences (endocrinology section) and NNF Center for Basic Metabolic Research (translational metabolic physiology section), Faculty of Health and Medical Sciences; University of Copenhagen; Copenhagen Denmark

Publisher

Wiley

Subject

Physiology,Physiology (medical),Nutrition and Dietetics

Reference32 articles.

1. Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal mechanisms;Balkan;Am J Physiol Regul Integr Comp Physiol,2000

2. Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo;Deacon;J Clin Endocrinol Metab,1995

3. Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in the anesthetized pig;Deacon;Am J Physiol Endocrinol Metab,1996

4. A good practice guide to the administration of substances and removal of blood, including routes and volumes;Diehl;J Appl Toxicol,2001

5. Biogenesis of plasma membrane glycoproteins. Purification and properties of two rat liver plasma membrane glycoproteins;Elovson;J Biol Chem,1980

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