Tracking the motion of the K V 1.2 voltage sensor reveals the molecular perturbations caused by a de novo mutation in a case of epilepsy

Author:

Pantazis Antonios123ORCID,Kaneko Maki45ORCID,Angelini Marina1,Steccanella Federica1,Westerlund Annie M.6ORCID,Lindström Sarah H.2ORCID,Nilsson Michelle2,Delemotte Lucie6,Saitta Sulagna C.7,Olcese Riccardo189ORCID

Affiliation:

1. Division of Molecular Medicine Department of Anesthesiology & Perioperative Medicine David Geffen School of Medicine University of California at Los Angeles Los Angeles CA USA

2. Division of Neurobiology Department of Biomedical and Clinical Sciences (BKV) Linköping University Linköping Sweden

3. Wallenberg Center for Molecular Medicine Linköping University Linköping Sweden

4. Center for Personalized Medicine Children's Hospital, Los Angeles Los Angeles CA USA

5. Division of Genomic Medicine Department of Pathology Children's Hospital Los Angeles Los Angeles CA USA

6. Science for Life Laboratory Department of Applied Physics KTH Royal Institute of Technology Solna Sweden

7. Department of Obstetrics and Gynecology and Division of Medical Genetics Department of Pediatrics David Geffen School of Medicine University of California at Los Angeles Los Angeles CA USA

8. Department of Physiology David Geffen School of Medicine University of California at Los Angeles Los Angeles CA USA

9. Brain Research Institute David Geffen School of Medicine University of California at Los Angeles Los Angeles CA USA

Funder

American Heart Association

Knut och Alice Wallenbergs Stiftelse

Science for Life Laboratory

Publisher

Wiley

Subject

Physiology

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