Current Status of Carcinogenicity Assessment of Peroxisome Proliferator-Activated Receptor Agonists by the US FDA and a Mode-of-Action Approach to the Carcinogenic Potential
Author:
Affiliation:
1. Drug Safety Research Laboratories, Eisai Co., Ltd.
Publisher
Japanese Society of Toxicologic Pathology
Subject
Toxicology,Pathology and Forensic Medicine
Link
http://www.jstage.jst.go.jp/article/tox/20/4/20_4_197/_pdf
Reference32 articles.
1. 1. Fiévet C, Fruchart J-C, and Staels B. PPAR α and PPAR γ dual agonists for the treatment of type 2 diabetes and the metabolic syndrome. Curr Opin Pharmacol. 6: 606-614. 2006.
2. 2. Shulman AI and Mangelsdorf DJ. Retinoid X receptor hererodimers in the metabolic syndrome. N Engl J Med. 353: 604-615. 2005.
3. The Mechanisms of Action of PPARs
4. 5. Peraza MA, Burdick AD, Marin HE, Gonzalez FJ, and Peters JM. The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR). Toxicl Sci. 90: 269-295. 2006.
Cited by 24 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Therapeutic Potential of PPARs in Alzheimer’s Disease;Current Thoughts on Dementia;2022
2. Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis;Journal of Medicinal Chemistry;2021-05-14
3. Toxicology and Nonclinical Safety Assessment in Pharmaceutical Discovery and Development;Burger's Medicinal Chemistry and Drug Discovery;2021-04-28
4. Nuclear Hormone Receptor Medicinal Chemistry;Burger's Medicinal Chemistry and Drug Discovery;2021-04-26
5. Preclinical Toxicology Evaluation;Early Drug Development;2018-08-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3