Phosphatidic Acid Interacts with a MYB Transcription Factor and Regulates Its Nuclear Localization and Function in Arabidopsis-Reference-Cited by-同舟云学术

Phosphatidic Acid Interacts with a MYB Transcription Factor and Regulates Its Nuclear Localization and Function in Arabidopsis

Published:2013-12-01 Issue:12 Volume:25 Page:5030-5042
ISSN:1532-298X
Container-title:The Plant Cell
language:en
Short-container-title:

Author:

Yao Hongyan¹²³⁴,Wang Geliang¹²,Guo Liang¹²,Wang Xuemin¹²

Affiliation:

1. Department of Biology, University of Missouri, St. Louis, Missouri 63121

2. Donald Danforth Plant Science Center, St. Louis, Missouri 63132

3. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai 200240, China

4. National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China

Abstract

Abstract Phosphatidic acid (PA) has emerged as a class of cellular mediators involved in various cellular and physiological processes, but little is known about its mechanism of action. Here we show that PA interacts with WEREWOLF (WER), a R2R3 MYB transcription factor involved in root hair formation. The PA-interacting region is confined to the end of the R2 subdomain. The ablation of the PA binding motif has no effect on WER binding to DNA, but abolishes its nuclear localization and its function in regulating epidermal cell fate. Inhibition of PA production by phospholipase Dζ also suppresses WER's nuclear localization, root hair formation, and elongation. These results suggest a role for PA in promoting protein nuclear localization.

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Plant Science

Link

http://academic.oup.com/plcell/article-pdf/25/12/5030/36958465/plcell_v25_12_5030.pdf

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