FORECASTING THE DEVELOPMENT OF PURULENT-INFLAMMATORY POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH OBSTRUCTIVE BOWEL OBSTRUCTION-Reference-Cited by-同舟云学术

FORECASTING THE DEVELOPMENT OF PURULENT-INFLAMMATORY POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH OBSTRUCTIVE BOWEL OBSTRUCTION

Published:2022 Issue:9 Volume:75 Page:2092-2097
ISSN:0043-5147
Container-title:Wiadomości Lekarskie
language:en
Short-container-title:Wiad Lek

Author:

Ivanova Julia V.¹,Gramatyuk Svitlana M.²,Vinnyk Yuriy O.³,Viun Sergii V.¹,Viun Tetiana I.¹,Goloborodko Mykola M.¹

Affiliation:

1. KHARKIV NATIONAL MEDICAL UNIVERSITY, KHARKIV, UKRAINE

2. INSTITUTE OF CELL BIOREHABILITATION OF THE MINISTRY OF HEALTH OF UKRAINE, KHARKIV, UKRAINE

3. KHARKIV ACADEMY OF POSTGRADUATE EDUCATION, KHARKIV, UKRAINE

Abstract

The aim: The purpose of the study is to improve the results of treatment of patients with acute intestinal obstruction of tumor origin by developing individualized surgical tactics considering the level of cryoglobulins. Materials and methods: 96 patients with ileus of tumor origin were studied. The mean age of patients was 54.7 ± 5.9 years. 30 patients were diagnosed with colorectal cancer, 35 patients - with sigmoid cancer, 13 patients - with cecum and ascending colon, 11 patients - with transverse colon cancer, and 7 patients with descending colon cancer. Isolation of cryoglobulins from blood serum was performed by the method of A. E. Kalovidoris with modifications. The content of Ig A, Ig M, Ig G, total Ig E in the serum was investigated using enzyme-linked immunosorbent assay systems “Granum-Ukraine”, the content of allergen-specific Ig E was investigated using enzyme-linked immunosorbent assay systems produced by “Microgen”. Results: As a result of treatment of 96 patients, it was found that the level of development of postoperative purulent complications was significantly influenced by the level of cryoglobulinemia and the volume of surgery (CMU, p <0.05). It was found that in patients with decompensated intestinal obstruction, the initial concentration of cryoglobulins was 16.4% higher than in the group with compensated intestinal obstruction (CMU, p <0,05). Conclusions: Determination of cryoglobulinemia on admission of patients with acute obstructive ileus of tumor origin is a simple and effective method for predicting the development of purulent-inflammatory complications in the postoperative period and can influence the choice of treatment tactics.

Publisher

ALUNA

Subject

General Medicine

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