Affiliation:
1. National Research Center for Hematology
Abstract
Introduction. Infections are among the most common complications after allogeneic hematopoietic stem cell transplantation.Aim — to provide a literature review on the main characteristics of infectious complications after allogenic hematopoietic stem cell transplantation and risk factors for their development.Main findings. Apart from direct factors such as neutropenia, hypogammaglobulinemia, and lymphopenia, there are indirect transplant-related factors such as conditioning regimen, transplant source, donor type, and graft-versus-host disease prophylaxis associated with higher infectious risk posttransplant. This review also presents the main characteristics of infections after allogeneic hematopoietic stem cell transplantation with a focus on bloodstream infections and provides an overview of the main transplant-related risk factors linked to their development.
Publisher
National Medical Research Center of Hematology of the Ministry of Health of the Russian Federation
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