Spatial Resolution of a small animal PET scanner using <sup>68</sup>Ga isotope-Reference-Cited by-同舟云学术

Spatial Resolution of a small animal PET scanner using <sup>68</sup>Ga isotope

Published:2024-04-24 Issue:2 Volume:12 Page:e2404
ISSN:2319-0612
Container-title:Brazilian Journal of Radiation Sciences
language:
Short-container-title:Braz. J. Rad. Sci.

Author:

Garcia Victoria M.,Silva A. C. M.,Gontijo Rodrigo Modesto Gadelha^ORCID,Vidal Ferreira Andréa^ORCID

Abstract

Nuclear Medicine is a modality that has been growing a lot in Brazil and in the world, bringing new radiopharmaceuticals and technologies for the diagnosis and treatment of diseases, making them more effective and accurate. In the development of new radiopharmaceuticals for use in positron emission tomography (PET), the preclinical studies step largely uses PET scanners dedicated to small animals. To achieve this, quality control tests must be carried out to ensure the efficiency of the equipment. Thus, this work aimed to evaluate the spatial resolution of the small animals PET scanner of the CDTN using the isotope 68Ga. In this sense, a microPET hot rod phantom and a commercial 68Ge/68Ga generator were used to obtain PET images. The analysis of the 68Ga-PET images of the simulator was carried out qualitatively and quantitatively and revealed that the spatial resolution of the system using the 68Ga is 3.5 mm.

Publisher

Sociedade Brasilieira de Protecao Radiologica - SBPR

Reference12 articles.

1. CNEN. Comissão Nacional de Energia Nuclear. Instalações de Medicina Nuclar Autorizadas. Available at: https://appasp2019.cnen.gov.br//seguranca/cons-ent-prof/entidades-aut-cert.asp. Last accessed: 25 July 2023.

2. CNEN. Comissão Nacional de Energia Nuclear. Relatório de Gestão CNEN 2022. Available at: https://www.gov.br/cnen/pt-br/acesso-a-informacao/transparencia-e-prestacaodecontas/arquivos_prestacaodecontas/relatoriodegestaocnen2022_publicado2.pdf/view. Last accessed: 25 July 2023.

3. GONTIJO, R.M.G.; et al. Performance based on NEMA NU-4 2008 Standard of CDTN/CNEN’s Small Animal PET Scanner. Brazilian Journal of Radiation Sciences, Belo Horizonte, v.10, n. 3, p. 1-17, 2022.

4. SAHA, G.B. Biological Tests. Basics of PET Imaging: Physics, Chemistry, and Regulations. Ohio, US: Springer Publishing Co, 2015. 3th ed., p. 121, ISBN 978-1-4899-8471-5.

5. CDTN. Centro de Desenvolvimento da Tecnologia Nuclear. Belo Horizonte, MG, Brazil. Available at: https://www.cdtn.br. Last accessed: 25 July 2023.