Molecular Mechanism of High Hemoglobin F Production in Southeast Asian-Type Hereditary Persistence of Fetal Hemoglobin

Author:

Changsri Khaimuk,Akkarapathumwong Varaporn,Jamsai Duangporn,Winichagoon Pranee,Fucharoen Suthat

Publisher

Springer Science and Business Media LLC

Subject

Hematology

Reference41 articles.

1. Wood WG. Hereditary persistence of fetal hemoglobin and δβ°-thalassemia. In: Steinberg MH, Forget BG, Higgs DR, et al, eds. Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management. Cambridge, UK: Cambridge University Press; 2001:356-388.

2. Forget BG. Molecular basis of hereditary persistence of fetal hemoglobin. Ann N Y Acad Sci. 1998;850:38-44.

3. Vitale M, Di Marzo R, Calzolari R, et al. Evidence for a globin promoter-specific silencer element located upstream of the human δ-globin gene. Biochem Biophys Res Commun. 1994;204:413-418.

4. Mantovani R, Malgaretti N, Nicolis S, Ronchi A, Giglioni B, Ottolenghi S. The effects of HPFH mutations in the human γ-globin promoter on binding of ubiquitous and erythroid specific nuclear factors. Nucleic Acids Res. 1988;16:7783-7797.

5. Mantovani R, Superti-Furga G, Gilman J, Ottolenghi S. The deletion of the distal CCAAT box region of the Aγ-globin gene in black HPFH abolishes the binding of the erythroid specific protein NFE3 and of the CCAAT displacement protein. Nucleic Acids Res. 1989;17:6681-6691.

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