The Myeloid Features of BXH2 Leukemias May Result from the Lack of One Copy of the Repetitive Sequence in the Long Terminal Repeat Viral Enhancer

Author:

Huang Liqun,Osato Motomi,Yanagida Masatoshi,Yamashita Namiko,Ito Yoshiaki

Publisher

Springer Science and Business Media LLC

Subject

Hematology

Reference6 articles.

1. Bedigian HG, Johnson DA, Jenkins NA, Copeland NG, Evans R. Spontaneous and induced leukemias of myeloid origin in recombinant inbred BXH mice. J Virol. 1984;51:586-594.

2. Turcotte K, Gauthier S, Mitsos LM, et al. Genetic control of myeloproliferation in BXH-2 mice. Blood. 2004;103:2343-2350.

3. Turcotte K, Gauthier S, Tuite A, Mullick A, Malo D, Gros P. A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 mice. J Exp Med. 2005;201:881-890.

4. Yamashita N, Osato M, Huang L, et al. Haploinsufficiency of Runx1/AML1 promotes myeloid features and leukaemogenesis in BXH2 mice. Br J Haematol. 2005;131:495-507.

5. Sorensen KD, Quintanilla-Martinez L, Kunder S, Schmidt J, Pedersen FS. Mutation of all Runx (AML1/core) sites in the enhancer of T-lymphomagenic SL3-3 murine leukemia virus unmasks a significant potential for myeloid leukemia induction and favors enhancer evolution toward induction of other disease patterns. J Virol. 2004;78:13216-13231.

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