Abstract
As a consequence of the fact that most bacteria types show increasing resistance to the conventional drugs, chemists and biochemists keep on trying to synthesize new potential medicines and to test their antibacterial activity. Under these circumstances, the present work’s goal is to present the synthesis, the preliminary analysis and antibacterial tests’ results for two structurally-related ligands belonging to the benzenesulfonamides' class, as well as for the two complex compounds formed by them through coordination to divalent zinc. Because of the usually high hepatotoxicity exhibited by benzenesulfonamides, they are unlikely suitable for human medical purposes, but they might present possibilities to be used as veterinary drugs. Consequently, we have focused on the possibility for our newly synthesized substances to be used in the treatment of urinary- and gastrointestinal tract bacterial infections, as well as galactophore channels’ infections, on equine and cattle; actually, for that matter, all pathogenic agents were sampled from horses or cows suffering from different infectious diseases (from urinary- or gastrointestinal tract or from females’ galactophore channels).