A Simple Test Identifies Selection on Complex Traits

Author:

Beissinger Tim123,Kruppa Jochen45,Cavero David6,Ha Ngoc-Thuy4,Erbe Malena7,Simianer Henner4

Affiliation:

1. Plant Genetics Research Unit, U. S. Department of Agriculture–Agricultural Research Service, Columbia, Missouri 65211

2. Division of Biological Sciences, University of Missouri, Columbia, Missouri 65211

3. Division of Plant Sciences, University of Missouri, Columbia, Missouri 65211

4. Center for Integrated Breeding Research, University of Göttingen, 37075, Germany

5. Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover, 30559, Germany

6. H&N International, 27472 Cuxhaven, Germany

7. Institute for Animal Breeding, Bavarian State Research Centre for Agriculture, 85586 Grub, Germany

Abstract

Abstract Important traits are often controlled by a large number of genes that each impact a small proportion of total variation; however, the majority of tools in population genomics are designed to identify single genes...

Publisher

Oxford University Press (OUP)

Subject

Genetics

Reference54 articles.

1. Constructing genomic maps of positive selection in humans: where do we go from here?;Akey;Genome Res.,2009

2. Genetics of body-weight regulation.;Barsh;Nature,2000

3. Recent demography drives changes in linked selection across the maize genome.;Beissinger;Nat. Plants,2016

4. A population genetic signal of polygenic adaptation.;Berg;PLoS Genet.,2014

5. Polygenic adaptation has impacted multiple anthropometric traits.;Berg;bioRxiv,2017

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