Development of a Novel Humanized Monoclonal Antibody to Secreted Frizzled-Related Protein-2 That Inhibits Triple-Negative Breast Cancer and Angiosarcoma Growth In Vivo-Reference-Cited by-同舟云学术

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Development of a Novel Humanized Monoclonal Antibody to Secreted Frizzled-Related Protein-2 That Inhibits Triple-Negative Breast Cancer and Angiosarcoma Growth In Vivo

Published:2019-09-12 Issue:13 Volume:26 Page:4782-4790
ISSN:1068-9265
Container-title:Annals of Surgical Oncology
language:en
Short-container-title:Ann Surg Oncol

Author:

Garcia Denise,Nasarre Patrick,Bonilla Ingrid V.,Hilliard Eleanor,Peterson Yuri K.,Spruill Laura,Broome Anne-Marie,Hill Elizabeth G.,Yustein Jason T.,Mehrotra Shikhar,Klauber-DeMore Nancy

Funder

St. Baldwick's Foundation to JTY

Hollings Cancer Center, Medical University of South Carolina

U.S. Department of Defense

NIH Clinical Center

Sarcoma Foundation of America

Cancer Prevention and Research Institute of Texas

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Surgery

Link

http://link.springer.com/content/pdf/10.1245/s10434-019-07800-2.pdf

Reference38 articles.

1. Kawano Y, Kypta R. Secreted antagonists of the Wnt signalling pathway. J Cell Sci. 2003;116(Pt 13):2627–34.

2. Yamamura S, Kawakami K, Hirata H, et al. Oncogenic functions of secreted frizzled-related protein 2 in human renal cancer. Mol Cancer Ther. 2010;9(6):1680–7.

3. Esteve P, Sandonis A, Ibanez C, Shimono A, Guerrero I, Bovolenta P. Secreted frizzled-related proteins are required for Wnt/beta-catenin signalling activation in the vertebrate optic cup. Development. 2011;138(19):4179–84.

4. Gehmert S, Sadat S, Song YH, Yan Y, Alt E. The anti-apoptotic effect of IGF-1 on tissue resident stem cells is mediated via PI3-kinase dependent secreted frizzled related protein 2 (Sfrp2) release. Biochem Biophys Res Commun. 2008;371(4):752–5.

5. Lee JL, Chang CJ, Wu SY, Sargan DR, Lin CT. Secreted frizzled-related protein 2 (SFRP2) is highly expressed in canine mammary gland tumors but not in normal mammary glands. Breast Cancer Res Treat. 2004;84(2):139–49.

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1. Identification of Genes Crucial for Biological Processes in Breast Cancer Liver Metastasis Relapse;International Journal of Molecular Sciences;2024-05-16

2. Secreted frizzled related-protein 2 is prognostic for human pancreatic cancer patient survival and is associated with fibrosis;Cancer Biomarkers;2023-11-20

3. Transcriptome analysis reveals differences in cell cycle, growth and migration related genes that distinguish fibroblasts derived from pre-invasive and invasive breast cancer;Frontiers in Oncology;2023-04-06

4. Expression Profile of Genes Encoding Proteins Involved in Regulation of Vasculature Development and Heart Muscle Morphogenesis—A Transcriptomic Approach Based on a Porcine Model;International Journal of Molecular Sciences;2021-08-16

5. Overcoming PD-1 Inhibitor Resistance with a Monoclonal Antibody to Secreted Frizzled-Related Protein 2 in Metastatic Osteosarcoma;Cancers;2021-05-30

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