Critical Role of Preoperative Hyperglycemia in Association with GFAT-1 Expression in Resected Pancreatic Cancer

Author:

Kohara Yuichiro,Yasuda Satoshi,Nagai Minako,Nakamura Kota,Matsuo Yasuko,Terai Taichi,Doi Shunsuke,Sakata Takeshi,Sho Masayuki

Publisher

Springer Science and Business Media LLC

Reference27 articles.

1. National Cancer Institute. Bethesda. SEER Cancer Stat Facts: Pancreatic Cancer. Retrieved 23 April 2024 at https://seer.cancer.gov/statfacts/html/pancreas.html

2. Liu Y, Cao Y, Pan X, et al. O-GlcNAc elevation through activation of the hexosamine biosynthetic pathway enhances cancer cell chemoresistance. Cell Death Dis. 2018;9:485.

3. Ma YS, Yang IP, Tsai HL, et al. High glucose modulates antiproliferative effect and cytotoxicity of 5-fluorouracil in human colon cancer cells. DNA Cell Biol. 2014;33:64–72.

4. Ikemura M, Hashida T. Effect of hyperglycemia on antitumor activity and survival in tumor-bearing mice receiving oxaliplatin and fluorouracil. Anticancer Res. 2017;37:5463–8.

5. Qiu J, Zheng Q, Meng X. Hyperglycemia and chemoresistance in breast cancer: from cellular mechanisms to treatment response. Front Oncol. 2021;11:628359.

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