<strong>Ti</strong>及钛合金表面改性在生物医用领域的研究进展

doi:10.11900/0412.1961.2022.00150

金属学报

2022, Vol. 58

Issue (7): 837-856 DOI: 10.11900/0412.1961.2022.00150

综述

本期目录 | 过刊浏览

Ti及钛合金表面改性在生物医用领域的研究进展

崔振铎, 朱家民, 姜辉, 吴水林, 朱胜利(

)

天津大学材料科学与工程学院天津 300350

Research Progress of the Surface Modification of Titanium and Titanium Alloys for Biomedical Application

CUI Zhenduo, ZHU Jiamin, JIANG Hui, WU Shuilin, ZHU Shengli(

)

School of Materials Science and Engineering, Tianjin University, Tianjin 300350, China

引用本文:

崔振铎, 朱家民, 姜辉, 吴水林, 朱胜利. Ti及钛合金表面改性在生物医用领域的研究进展[J]. 金属学报, 2022, 58(7): 837-856.
Zhenduo CUI, Jiamin ZHU, Hui JIANG, Shuilin WU, Shengli ZHU. Research Progress of the Surface Modification of Titanium and Titanium Alloys for Biomedical Application[J]. Acta Metall Sin, 2022, 58(7): 837-856.

全文: PDF(2104 KB) HTML

摘要:

Ti及钛合金作为人体硬组织的主要替代物之一,在生物医用领域应用广泛。为了更好地满足Ti及钛合金在人体中植入后的安全、舒适、耐久等需求,Ti及钛合金表面改性处理成为了研究的热点。本文基于Ti及钛合金的基础性能和存在的问题,从表面改性提高其力学性能、生物相容性、抑菌/抗菌性能等方面综述了Ti及钛合金表面改性在生物医用领域的研究进展,并提出了面临的挑战以及发展方向的建议。

关键词 ： Ti, 钛合金, 表面改性, 生物医用, 生物相容性, 抗菌

Abstract：

Titanium and titanium alloys have widely been used in biomedical applications as main substitutes for hard human tissues. To better meet the needs of safety, comfort, and durability of titanium and titanium alloys after implantation in the human body, the surface modification treatment of titanium and titanium alloys has become a research hotspot. In this review, based on the basic properties and existing problems of titanium and titanium alloys, the methods of surface modification for titanium and titanium alloys are introduced to improve their mechanical properties, biocompatibility, and bacteriostatic/antibacterial properties. Furthermore, the current challenges and prospects have been presented in this paper.

Key words： Ti titanium alloy surface modification biomedical application biocompatibility antibacterial

收稿日期: 2022-03-30

ZTFLH:

TG178

基金资助:国家自然科学基金项目(51771131);国家自然科学基金项目(52173182)

作者简介: 崔振铎,男,1962年生,教授,博士

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https://www.ams.org.cn/CN/10.11900/0412.1961.2022.00150 或 https://www.ams.org.cn/CN/Y2022/V58/I7/837

图1 电弧熔融制备钛合金及其应用示意图、钛合金高温气体热处理示意图

图2 放电等离子烧结制备Ti-Mg合金和钛合金激光表面改性示意图

图3 喷砂、酸蚀及其组合,3D打印及激光表面纹理化示意图

图4 等离子喷涂制备涂层、脉冲激光沉积制备涂层、阳极氧化/等离子体电解氧化/微弧氧化表面改性及基因治疗示意图

图5 超疏水性抑菌、亲水性抑菌、表面仿生结构抑菌示意图及药物抗菌、正电荷物质抗菌、金属离子抗菌示意图

图6 光热抗菌、光动力抗菌、光声抗菌示意图

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