Celiac disease in children and adolescents with Down syndrome: behavioural, adaptive and sleep profiles

Author:

Fucà E.1ORCID,Costanzo F.1ORCID,Galassi P.1ORCID,Celestini L.2ORCID,Valentini D.2ORCID,Vicari S.13ORCID

Affiliation:

1. Child and Adolescent Neuropsychiatry Unit Bambino Gesù Children's Hospital, IRCCS Rome Italy

2. Pediatric Unit, Pediatric Emergency Department Bambino Gesù Children's Hospital, IRCCS Rome Italy

3. Department of Life Science and Public Health Catholic University of the Sacred Heart Rome Italy

Abstract

AbstractBackgroundIndividuals with Down syndrome (DS) exhibit higher risk for celiac disease (CD) than general population. Although literature suggests CD could be associated with behavioural problems in both paediatric and adult age, such association has been poorly explored in children and adolescents DS. Therefore, the current study aimed to investigate differences in emotional/behavioural difficulties, adaptive skills and sleep problems between children with DS with and without CD.MethodsData were retrospectively collected from a database including data from 381 individuals with DS (3–18 years). The final sample included 65 participants, 27 with co‐occurring CD and 38 age, IQ, sex and body mass index‐matched controls without CD. Emotional/behavioural difficulties, adaptive skills and sleep problems were assessed through parent report questionnaires.ResultsNo group differences emerged in emotional/behavioural difficulties, whereas participants in the CD group showed better adaptive skills in the practical domain than control group. Weak differences emerged in sleep problems.ConclusionsYouth with DS and co‐occurring CD do not exhibit more emotional and behavioural problems than youth with DS without co‐occurring CD but exhibit better adaptive skills in the practical domain.

Funder

Ministero della Salute

Publisher

Wiley

Reference54 articles.

1. Triple diagnosis of Crohn's disease, celiac disease, and eosinophilic esophagitis in a child with Siderius‐Hamel syndrome;Ahlawat R.;WMJ: Official Publication of the State Medical Society of Wisconsin,2019

2. European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten‐related disorders

3. Sleep Disturbances Are Commonly Reported Among Patients Presenting to a Gastroenterology Clinic

4. Prevalence and Clinical Picture of Celiac Disease in Italian Down Syndrome Patients: A Multicenter Study

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3