Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin

Author:

Volt Huayqui12,García José A.12,Doerrier Carolina12,Díaz-Casado María E.12,Guerra-Librero Ana12,López Luis C.12,Escames Germaine12,Tresguerres Jesús A.3,Acuña-Castroviejo Darío124

Affiliation:

1. Centro de Investigación Biomédica; Parque Tecnológico de Ciencias de la Salud; Universidad de Granada; Granada Spain

2. Departamento de Fisiología; Facultad de Medicina; Universidad de Granada; Granada Spain

3. Departamento de Fisiología; Facultad de Medicina; Universidad Complutense de Madrid; Madrid Spain

4. Unidad de Gestión Clínica de Laboratorios; Hospital Universitario San Cecilio; Granada Spain

Funder

Instituto de Salud Carlos III

Consejería de Innovación, Ciencia y Empresa

Publisher

Wiley

Subject

Endocrinology

Reference83 articles.

1. Sepsis-induced cardiac mitochondrial damage and potential therapeutic interventions in the elderly;Zang;Aging Dis,2014

2. Sepsis in old age: review of human and animal studies;Starr;Aging Dis,2014

3. Pathophysiology of sepsis in the elderly: clinical impact and therapeutic considerations;de Gaudio;Curr Drug Targets,2009

4. Sepsis and the heart;Hunter;Br J Anaesth,2010

5. Assessment of the worldwide burden of critical illness: the intensive care over nations (ICON) audit;Vincent;Lancet Respir Med,2014

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