Efficacy and safety of treatment with biologicals (benralizumab, dupilumab and omalizumab) for severe allergic asthma: A systematic review for the EAACI Guidelines ‐ recommendations on the use of biologicals in severe asthma-Reference-Cited by-同舟云学术

Efficacy and safety of treatment with biologicals (benralizumab, dupilumab and omalizumab) for severe allergic asthma: A systematic review for the EAACI Guidelines ‐ recommendations on the use of biologicals in severe asthma

Published:2020-05 Issue:5 Volume:75 Page:1043-1057
ISSN:0105-4538
Container-title:Allergy
language:en
Short-container-title:Allergy

Author:

Agache Ioana¹^ORCID,Rocha Claudio²,Beltran Jessica²,Song Yang²,Posso Margarita²³,Solà Ivan²,Alonso‐Coello Pablo²⁴,Akdis Cezmi⁵^ORCID,Akdis Mubeccel⁵^ORCID,Canonica Giorgio W.⁶,Casale Thomas⁷^ORCID,Chivato Tomas⁸,Corren Jonathan⁹,Del Giacco Stefano¹⁰,Eiwegger Thomas¹¹¹²¹³^ORCID,Firinu Davide¹⁰^ORCID,Gern James E.¹⁴,Hamelmann Eckard¹⁵^ORCID,Hanania Nicola¹⁶,Mäkelä Mika¹⁷,Martín Irene Hernández¹⁸,Nair Parameswaran¹⁹²⁰^ORCID,O'Mahony Liam²¹^ORCID,Papadopoulos Nikolaos G.²²²³^ORCID,Papi Alberto²⁴,Park Hae‐Sim²⁵^ORCID,Pérez de Llano Luis²⁶^ORCID,Quirce Santiago²⁷,Sastre Joaquin²⁸^ORCID,Shamji Mohamed²⁹³⁰^ORCID,Schwarze Jurgen³¹,Canelo‐Aybar Carlos²⁵,Palomares Oscar³²^ORCID,Jutel Marek³³³⁴

Affiliation:

1. Faculty of Medicine Transylvania University Brasov Romania

2. Iberoamerican Cochrane Centre Department of Clinical Epidemiology and Public Health Biomedical Research Institute Sant Pau (IIB Sant Pau) Barcelona Spain

3. Department of Epidemiology and Evaluation IMIM (Hospital del Mar Medical Research Institute) Barcelona Spain

4. CIBER de Epidemiología y Salud Pública (CIBERESP) Barcelona Spain

5. Swiss Institute of Allergy and Asthma Research (SIAF) University of Zurich Davos Switzerland

6. Personalized Medicine, Asthma and Allergy Humanitas Clinical and Research Center IRCCS Rozzano Italy

7. Division of Allergy and Immunology University of South Florida Morsani College of Medicine Tampa FL USA

8. School of Medicine University CEU San Pablo Madrid Spain

9. David Geffen School of Medicine at UCLA Los Angeles CA USA

10. Department of Medical Sciences and Public Health University of Cagliari ItalyMonserrato

11. Translational Medicine Program, Research Institute Hospital for Sick Children Toronto ON Canada

12. Department of Immunology University of Toronto Toronto ON Canada

13. Division of Immunology and Allergy Food Allergy and Anaphylaxis Program The Hospital for Sick Children Departments of Paediatrics and Immunology University of Toronto Toronto ON Canada

14. Department of Pediatrics University of Wisconsin School of Medicine and Public Health Madison WI USA

15. Klinik für Kinder‐ und Jugendmedizin Kinderzentrum Bethel Bielefeld Germany

16. Section of Pulmonary, Critical Care and Sleep Medicine Baylor College of Medicine Houston Texas USA

17. Skin and Allergy Hospital Helsinki University Hospital and University of Helsinki Helsinki Finland

18. Department of Allergy Hospital Universitario La Paz Madrid Spain

19. Division of Respirology Department of Medicine McMaster University Hamilton ON Canada

20. Firestone Institute for Respiratory Health St Joseph's Healthcare Hamilton ON Canada

21. Departments of Medicine and Microbiology APC Microbiome Ireland University College Cork Cork Ireland

22. Division of Infection Immunity & Respiratory Medicine University of Manchester Manchester UK

23. Allergy Department 2nd Pediatric Clinic National Kapodistrian University of Athens Athens Greece

24. Research Center on Asthma and COPD Department of Medical Sciences University of Ferrara Ferrara Italy

25. Department of Allergy and Clinical Immunology Ajou University Suwon South Korea

26. Department of Respiratory Medicine Hospital Lucus Augusti Lugo Spain

27. Department of Allergy La Paz University Hospital IdiPAZ CIBER of Respiratory Diseases (CIBERES) Universidad Autónoma de Madrid Madrid Spain

28. Universidad Autónoma de Madrid Facultad de Medicina Madrid Spain

29. Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Inflammation Repair, Development National Heart and Lung Institute London UK

30. Imperial College NIHR Biomedical Research Centre UK Centre in Allergic Mechanisms of Asthma London UK

31. Centre for Inflammation Research Child Life and Health The University of Edinburgh Edinburgh UK

32. Department of Biochemistry and Molecular Biology Chemistry School Complutense University of Madrid Madrid Spain

33. Department of Clinical Immunology Wroclaw Medical University Wroclaw Poland

34. All‐MED Medical Research Institute Wroclaw Poland

Funder

European Academy of Allergy and Clinical Immunology

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/all.14235

Reference106 articles.

1. https://ginasthma.org/wp‐content/uploads/2019/06/GINA‐2019‐main‐report‐June‐2019‐wms.pdf. Accessed December 23 2019.

2. EAACI Guidelines on Allergen Immunotherapy: House dust mite‐driven allergic asthma

3. Provocative proposal for a revised nomenclature for allergy and other hypersensitivity diseases

4. Immunologic mechanisms in asthma

5. Is IgE or eosinophils the key player in allergic asthma pathogenesis? Are we asking the right question?

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