1. Division of Endocrinology and Metabolism Department of Internal Medicine National Cheng Kung University Hospital College of Medicine National Cheng Kung University Tainan Taiwan
2. Department of Pediatrics National Cheng Kung University Hospital College of Medicine National Cheng Kung UniversityTainan Taiwan
3. Institute of Clinical Medicine College of Medicine National Cheng Kung University Tainan Taiwan
4. Institute of Basic Medical Sciences College of Medicine National Cheng Kung UniversityTainan Taiwan
5. Division of Gastroenterology Department of Internal Medicine National Cheng Kung University Hospital College of Medicine National Cheng Kung University Tainan Taiwan
6. Department of Nursing Shu‐Zen Junior College of Medicine and Management Kaohsiung Taiwan
7. Department of Internal Medicine Tainan Hospital Ministry of Health and Welfare Tainan Taiwan