Phosphorylation of trans‐active response DNA‐binding protein‐of 43 kDa promotes its cytoplasmic aggregation and modulates its function in tau mRNA stability and exon 10 alternative splicing-Reference-Cited by-同舟云学术

Phosphorylation of trans‐active response DNA‐binding protein‐of 43 kDa promotes its cytoplasmic aggregation and modulates its function in tau mRNA stability and exon 10 alternative splicing

Published:2021-07-10 Issue:3 Volume:158 Page:766-778
ISSN:0022-3042
Container-title:Journal of Neurochemistry
language:en
Short-container-title:J. Neurochem.

Author:

Wu Ruozhen¹²,Zhou Dingwei¹²,Shen Xin¹,Chen Feng¹,Liu Fei²^ORCID,Gu Jianlan¹²^ORCID

Affiliation:

1. Key Laboratory of Neuroregeneration and Ministry of Education of Jiangsu Co‐innovation Center of Neuroregeneration NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products Department of Biochemistry and Molecular Biology School of Medicine Nantong University Nantong Jiangsu China

2. Department of Neurochemistry Inge Grundke‐Iqbal Research Floor New York State Institute for Basic Research in Developmental Disabilities Staten Island NY USA

Funder

Nantong University

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jnc.15450

Reference38 articles.

1. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

2. Phosphorylated TDP-43 in Alzheimer’s disease and dementia with Lewy bodies