L‐asparaginase isolated from Streptomyces ansochromogenes promotes Th1 profile and activates CD 8 + T cells in human PBMC : an in vitro investigation

Author:

Silva Lacerda G.R.1,Melo C.M.L.2,Araújo Soares A.K.3,Moreira L.R.3,Coriolano M.C.4,Souza Lima G.M.1,Napoleão T.H.4,Lorena V.M.B.3ORCID,Oliveira da Silva L.A.1,Nascimento S.C.1

Affiliation:

1. Department of Antibiotics Federal University of Pernambuco Pernambuco Brazil

2. Laboratory of Immunological and Antitumor Analyzes Department of Antibiotics Federal University of Pernambuco Pernambuco Brazil

3. Laboratory of Immunoparasitology – Aggeu Magalhães Research Center (CPqAM) Oswaldo Cruz Foundation (FIOCRUZ) Pernambuco Brazil

4. Laboratory of Glycoproteins – Department of Biochemistry Federal University of Pernambuco Pernambuco Brazil

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Reference43 articles.

1. L‐asparaginase gene – A therapeutic approach towards drugs for cancer cell;Ahmad N.;Int J Biosci,2012

2. Asparaginase (native ASNase or pegylated ASNase) in the treatment of acute lymphoblastic leukemia;Avramis V.I.;Int J Nanomed,2006

3. Production, isolation, and purification of L‐asparaginase from Aspergillus terreus using submerged fermentation;Balasubramanian K.;Int J Adv Pharm Res,2012

4. Taxonomy, Physiology, and Natural Products of Actinobacteria

5. Bioactive products from streptomyces

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