Affiliation:
1. Department of Oral Pathology, Oral Medicine and Maxillofacial Imaging, Goldschleger School of Dental Medicine, Sackler Faculty of Medicine Tel‐Aviv University Israel Tel‐Aviv Israel
2. Department of Internal Medicine Tel‐Aviv Sourasky Medical Centre Tel‐Aviv Israel
3. Sackler Faculty of Medicine Tel‐Aviv University Ramat Aviv Tel‐Aviv Israel
4. Health Division Maccabi Healthcare Services Tel‐Aviv Israel
Abstract
AbstractAimsThe aim of the study was to analyze objective and subjective olfactory/gustatory function in post‐COVID‐19 infection (PCI).Materials and MethodsPatients with past PCR‐confirmed COVID‐19 infection and persistent olfactory/gustatory complaints were investigated. Olfactory threshold and identification, gustatory detection, identification, and magnitude scaling were tested.ResultsA total of 42 PCI subjects were compared to 41 age‐ and gender‐matched controls with no COVID‐19 history. All PCI tested had mild COVID‐19 disease. Mean interval between COVID‐19 confirmations to testing was 7.4 ± 3.1 months. PCI subjects complained of combined dysfunction in 85.7%, isolated olfactory or gustatory dysfunction in 7.1% each. Combined complaints were significantly higher in PCI (p < 0.001). Objective testing showed significantly higher prevalence of dysfunction in PCI versus controls for hyposmia (73.8%, 12.2%), anosmia (11.9%, 0%), odor identification (68.5%, 83.0%), hypogeusia (23% and 2.4%, respectively), and impaired magnitude scaling, (p < 0.05). All PCI subjects with hypogeusia had abnormal gustatory magnitude scaling.ConclusionsWhile most PCI subjects complained of combined gustatory and olfactory dysfunction, objective testing showed in the majority an isolated single sense dysfunction, with a low level of agreement between subjective and objective findings.Abnormal objective results for all olfactory and gustatory functions tested may suggest a central rather than peripheral mechanism, although concomitant mechanisms cannot be excluded.
Subject
General Dentistry,Otorhinolaryngology
Cited by
1 articles.
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