Mechanism of induction of immune tolerance in experimental autoimmune encephalomyelitis by combination treatment with fingolimod plus pathogenic autoantigen-Reference-Cited by-同舟云学术

Mechanism of induction of immune tolerance in experimental autoimmune encephalomyelitis by combination treatment with fingolimod plus pathogenic autoantigen

Published:2014-08-22 Issue:1 Volume:6 Page:49-56
ISSN:1759-1961
Container-title:Clinical and Experimental Neuroimmunology
language:en
Short-container-title:Clin Exp Neuroimmunol

Author:

Yoshida Yuya¹,Mikami Norihisa²,Tsuji Takumi¹,Takada Yuki¹,Nakazawa Yuka¹,Dan Rie¹,Takatsuji Miku²,Fujita Tetsuro³,Tsujikawa Kazutake²,Kohno Takeyuki¹³

Affiliation:

1. Department of Pathological Biochemistry; Faculty of Pharmaceutical Sciences; Setsunan University; Osaka Japan

2. Laboratory of Molecular and Cellular Physiology; Graduate School of Pharmaceutical Sciences; Osaka University; Osaka Japan

3. Research Institute for Production and Development; Kyoto Japan

Publisher

Wiley

Subject

Clinical Neurology,Immunology and Microbiology (miscellaneous),Immunology,Neuroscience (miscellaneous)

Reference32 articles.

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3. FTY720 ameliorates MOG-induced experimental autoimmune encephalomyelitis by suppressing both cellular and humoral immune responses;Papadopoulos;J Neurosci Res,2010

4. Relapse of experimental autoimmune encephalomyelitis after discontinuation of FTY720 (Fingolimod) treatment, but not after combination of FTY720 and pathogenic autoantigen;Yoshida;Biol Pharm Bull,2011

5. Fingolimod (FTY720), sphingosine 1-phosphate receptor modulator, shows superior efficacy as compared with interferon-β in mouse experimental autoimmune encephalomyelitis;Chiba;Int Immunopharmacol,2011

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