<scp> <i>NOTCH1</i> </scp> mutation in chronic lymphocytic leukaemia is associated with an enhanced cell cycle <scp>G1</scp> /S transition and specific cyclin overexpression: Preclinical ground for targeted inhibition-Reference-Cited by-同舟云学术

NOTCH1 mutation in chronic lymphocytic leukaemia is associated with an enhanced cell cycle G1 /S transition and specific cyclin overexpression: Preclinical ground for targeted inhibition

Published:2022-12-27 Issue:3 Volume:201 Page:470-479
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:Br J Haematol

Author:

Carrillo‐Tornel Salvador¹^ORCID,Chen‐Liang Tzu Hua¹,Zurdo María¹,Puiggros Anna²³^ORCID,Gómez‐Llonín Andrea²³,García‐Malo María Dolores¹,Cuenca‐Zamora Ernesto José¹⁴,Ortuño Francisco José¹,López Ana María Hurtado¹^ORCID,Espinet Blanca²³^ORCID,Jerez Andrés¹⁴^ORCID

Affiliation:

1. Hematology and Medical Oncology Department Hospital Universitario Morales Meseguer, CRH‐IMIB, Universidad de Murcia Murcia Spain

2. Molecular Cytogenetics Laboratory. Pathology Service Hospital del Mar Barcelona Spain

3. Translational Research Group on Hematological Neoplasms Hospital del Mar Research Institute (IMIM) Barcelona Spain

4. CB15/00055‐CIBERER Murcia Spain

Funder

Fundación Española de Hematología y Hemoterapia

Gilead Sciences

Instituto de Salud Carlos III

European Commission

Publisher

Wiley

Subject

Hematology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.18609

Reference27 articles.

1. Chronic lymphocytic leukaemia: from genetics to treatment

2. Cell cycle phase distribution analysis in chronic lymphocytic leukaemia: a significant number of cells reside in early G1-phase

3. Overexpression of cyclin D2 in chronic B-cell malignancies

4. Prognostic Significance of the Cell Cycle Inhibitor p27Kip1 in Chronic B-Cell Lymphocytic Leukemia

5. Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27

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1. Uncovering NOTCH1 as a Promising Target in the Treatment of MLL-Rearranged Leukemia;International Journal of Molecular Sciences;2023-09-23

2. D-Type Cyclins in Development and Disease;Genes;2023-07-14