Granuloprival cerebellar cortical degeneration in a Yorkshire Terrier and Lagotto Romagnolo dog

Author:

Mignan Thomas1ORCID,Pumarola Martí2,Platt Simon3,James Matthew1,Pereira Marta4,Morey‐Matamalas Antonia4,Recio Alfredo5

Affiliation:

1. Dovecote Veterinary Hospital, 5 Delven Lane, Castle Donington Derby DE74 2LJ United Kingdom

2. Department of Animal Medicine and Surgery, Veterinary Faculty Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès) Barcelona 08193 Spain

3. CVS Teleneurology, 1 Owen Road Diss IP22 4ER United Kingdom

4. School of Veterinary Medicine and Science, University of Nottingham Sutton Bonington, Leicestershire LE12 5RD United Kingdom

5. Clínica Veterinaria Levante, Avenida de La Unión 61 San Javier, Murcia 30730 Spain

Abstract

AbstractGranuloprival degeneration is an uncommon form of cerebellar cortical degeneration (CCD). A 3‐month‐old Yorkshire Terrier and a 7‐month‐old Lagotto Romagnolo dog were presented with a history of progressive cerebellar dysfunction including wide‐based stance, cerebellar ataxia, intention tremors, and loss of menace response despite normal vision. Magnetic resonance imaging of the brain identified marked diffuse decrease of the cerebellum size. Euthanasia was performed in both cases because of progression of clinical signs. Histopathological examination identified marked diffuse thinning of the granular cell layer with almost complete loss of the granular cell neurons, providing a definitive diagnosis of granuloprival CCD. Granuloprival CCD should be considered as a differential diagnosis in Yorkshire Terrier and Lagotto Romagnolo dogs with post‐natal progressive clinical signs of cerebellar dysfunction.

Publisher

Wiley

Reference27 articles.

1. Canine Hereditary Ataxia

2. Postnatal cerebellar cortical degeneration in Labrador Retriever puppies;Perille AL;Canadian Vet J,1991

3. Cerebellar Abiotrophy Characterized by Granular Cell Loss in a Brittany

4. Cerebellar cortical degeneration in a Labrador Retriever;Bildfell RJ;Canadian Vet J,1995

5. Presumed immune-mediated cerebellar granuloprival degeneration in the Coton de Tuléar breed

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3