Organ xenotransplantation acceptance in veterinary students: A multicentric opinion study in Spain

Author:

Martínez‐Alarcón Laura123ORCID,Flores‐Medina Juan4,Ramis Guillermo12356ORCID,Gómez‐Laguna Jaime7,Moll Xavier8,Falceto Victoria9,San Román‐Ascaso Fidel10,San Román‐Llorens Fidel11,Quereda Juan José12,Herrero Juan Manuel6,Mendonça Livia13,Martin‐Barrasa José Luis1415,Fernández Olga María16,Muñoz Antonio6,Ramírez Pablo12356,Gutiérrez Pedro1718,López‐Chicheri Isabel4,López‐Navas Ana14ORCID,Ríos Antonio12356ORCID

Affiliation:

1. International Collaborative Donor Project Murcia Spain

2. Surgery Service, Transplant Unit Hospital Universitario Virgen de la Arrixaca Murcia Spain

3. Instituto Murciano de Investigación Biosanitaria (IMIB) Murcia Spain

4. Department of Psychology, Faculty of Medicine Catholic University of Murcia (UCAM) Murcia Spain

5. Department of Surgery Paediatrics, Obstetrics and Gynaecology University of Murcia Murcia Spain

6. Department of Animal Production Faculty of Veterinary Medicine University of Murcia Murcia Spain

7. Department of Anatomy and Comparative Pathology and Toxicology University of Córdoba Córdoba Spain

8. Faculty of Veterinary Medicine Autonomous University of Barcelona Barcelona Spain

9. Department of Animal Pathology Faculty of Veterinary Medicine University of Zaragoza Zaragoza Spain

10. Department of Animal Medicine and Surgery Faculty of Veterinaria Universidad Complutense de Madrid Madrid Spain

11. Department of Animal Pathology Faculty of Veterinary University of Zaragoza Zaragoza Spain

12. Department of Animal Production and Health Veterinary Public Health and Food Science and Technology Faculty of Veterinary University Cardenal Herrera‐CEU Valencia Spain

13. Faculty of Veterinary Universidade Federal de Goiás Goiania Brazil

14. Experimental Animal Facility Research Unit Hospital Universitario de Gran Canaria, Dr. Negrín Las Palmas de Gran Canaria, Arucas Spain

15. Animal Infectious Diseases and Ictiopatology University Institute of Animal Health (IUSA) University of Las Palmas de Gran Canaria Arucas Spain

16. Animalario libre de Patógenos Arrixaca‐Instituto Murciano de Investigación Biosanitaria (IMIB) Murcia Spain

17. Urology Service Complejo Hospitalario Universitario de Canarias La Laguna Santa Cruz de Tenerife Spain

18. Departmen of Surgery University of La Laguna San Cristóbal de la Laguna Tenerife Spain

Abstract

AbstractBackgroundThe shortage of available transplant organs has made it necessary to search for alternatives, one of which is xenotransplantation. However, the use of animal organs could face rejection from society and the personnel involved in its implementation. Objectives: (a) to analyze the attitudes of Veterinary Degree students in six Spanish Universities towards xenotransplantation; and (b) to determine the factors that affect its acceptance.MethodsOf the 2815 students surveyed in the degree program, 2683 valid surveys were obtained. Attitudes towards organ xenotransplantation were evaluated using a validated questionnaire of organ donation.ResultsIf xenotransplantation was confirmed as a clinical reality, 93% (n = 2493) of those surveyed would accept a xenotransplanted organ, whilst 7% would not. If the results of xenotransplantation were worse than those obtained with human donors and it entailed more risk, 12% (n = 318) would be in favor. 56% (n = 1497) of the students would accept a xenotransplantation provisionally pending the arrival of a human organ. Attitudes towards xenotransplantation were affected by the academic year in which a student was studying, with more favorable attitudes among students in the last year (88% in first year vs. 95% in fifth year; p < .001). More favorable attitudes are also observed depending on the attitude they have towards organ transplantation, with those students being more in favor of donating their organs when they die (94% vs. 88%; p < .001).ConclusionVeterinary students would have a very favorable attitude toward xenotransplantation if these animal organs functioned as well as human organs. Therefore, these students could play an important role in the future promotion of this technique.

Publisher

Wiley

Subject

Transplantation,Immunology

Reference49 articles.

1. First clinical‐grade porcine kidney xenotransplant using a human decedent model;Porrett PM;Am J Transplant,2022

2. Results of Two Cases of Pig-to-Human Kidney Xenotransplantation

3. Genetically Modified Porcine-to-Human Cardiac Xenotransplantation

4. First pig-to-human heart transplant: what can scientists learn?

5. System USRD.2020 USRDS Annual Data Report: Epidemiology of Kidney Disease in the United States. National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases;2020.

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3