Tim-4 inhibition of T-cell activation and T helper type 17 differentiation requires both the immunoglobulin V and mucin domains and occurs via the mitogen-activated protein kinase pathway

Author:

Cao Wei,Ryan Michelle,Buckley Deirdre,O’Connor Rosemary,Clarkson Michael R.

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference30 articles.

1. Identification of Tim-4 as a phosphatidylserine receptor;Miyanishi;Nature,2007

2. Inhibition of in vitro and in vivo T cell responses by recombinant human Tim-1 extracellular domain proteins;Mesri;Int Immunol,2006

3. TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation;Meyers;Nat Immunol,2005

4. Mechanisms of phosphatidylserine exposure, a phagocytic recognition signal, on apoptotic T lymphocytes;Verhoven;J Exp Med,1995

5. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers recognition and removal by macrophages;Fadok;J Immunol,1992

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