Affiliation:
1. Department of Medicine, University of Washington
2. VA Medical Center, Puget Sound Health Care System, Seattle, WA, USA
Abstract
Summary
OTHER THEMES PUBLISHED IN THIS IMMUNOLOGY IN THE CLINIC REVIEW SERIES
Allergy, Host Responses, Cancer, Autoinflammatory Diseases, Type 1 diabetes and viruses.
Historically, the development of type 2 diabetes has been considered not to have an autoimmune component, in contrast to the autoimmune pathogenesis of type 1 diabetes. In this review we will discuss the accumulating data supporting the concept that islet autoreactivity and inflammation is present in type 2 diabetes pathogenesis, and the islet autoimmunity appears to be one of the factors associated with the progressive nature of the type 2 diabetes disease process.
Publisher
Oxford University Press (OUP)
Subject
Immunology,Immunology and Allergy
Cited by
72 articles.
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