Design, synthesis, and biological evaluation of piperidinyl‐substituted [1,2,4]triazolo[1,5‐a]pyrimidine derivatives as potential anti‐HIV‐1 agents with reduced cytotoxicity-Reference-Cited by-同舟云学术

Design, synthesis, and biological evaluation of piperidinyl‐substituted [1,2,4]triazolo[1,5‐a]pyrimidine derivatives as potential anti‐HIV‐1 agents with reduced cytotoxicity

Published:2020-08-03 Issue:1 Volume:97 Page:67-76
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Huang Boshi¹^ORCID,Kang Dongwei¹,Tian Ye¹,Daelemans Dirk²,De Clercq Erik²,Pannecouque Christophe²,Zhan Peng¹^ORCID,Liu Xinyong¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry Key Laboratory of Chemical Biology (Ministry of Education) School of Pharmaceutical Sciences Shandong University Ji'nan China

2. Rega Institute for Medical Research Laboratory of Virology and Chemotherapy K.U.Leuven Leuven Belgium

Funder

National Natural Science Foundation of China

KU Leuven

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cbdd.13760

Reference23 articles.

1. Dithiocarbamate–thiourea hybrids useful as vaginal microbicides also show reverse transcriptase inhibition: Design, synthesis, docking and pharmacokinetic studies