3,4-Methylenedioxypyrovalerone prevents while methylone enhances methamphetamine-induced damage to dopamine nerve endings: β-ketoamphetamine modulation of neurotoxicity by the dopamine transporter
Author:
Affiliation:
1. Research & Development Service; John D. Dingell VA Medical Center; Detroit Michigan USA
2. Department of Psychiatry & Behavioral Neurosciences; Wayne State University School of Medicine; Detroit Michigan USA
Funder
Department of Veterans Affairs
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jnc.13048/fullpdf
Reference59 articles.
1. Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats;Aarde;Addict. Biol.,2013a
2. The novel recreational drug 3,4-methylenedioxypyrovalerone (MDPV) is a potent psychomotor stimulant: self-administration and locomotor activity in rats;Aarde;Neuropharmacology,2013b
3. Mephedrone, an abused psychoactive component of ‘bath salts’ and methamphetamine congener, does not cause neurotoxicity to dopamine nerve endings of the striatum;Angoa-Perez;J. Neurochem.,2012
4. Mephedrone does not damage dopamine nerve endings of the striatum, but enhances the neurotoxicity of methamphetamine, amphetamine, and MDMA;Angoa-Perez;J. Neurochem.,2013
5. Effects of combined treatment with mephedrone and methamphetamine or 3,4-methylenedioxymethamphetamine on serotonin nerve endings of the hippocampus;Angoa-Perez;Life Sci.,2014
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