1. Department of Cell and Systems Biology, University of Toronto, 25 Willcocks St, Toronto, Ontario, M5S 3B2 Canada;
2. Faculty of Science, University of Ontario Institute of Technology, 2000 Simcoe St North, Science Building UA4000, Oshawa, Ontario, L1H 7K4 Canada;
3. Centre for the Analysis of Genome Evolution & Function, University of Toronto, Toronto, Ontario, Canada