Prophylactic supplement with melatonin successfully suppresses the pathogenesis of periodontitis through normalizing RANKL/OPG ratio and depressing the TLR4/MyD88 signaling pathway

Author:

Renn Ting-Yi1,Huang Yung-Kai2,Feng Sheng-Wei2,Wang Hsiao-Wei3,Lee Wei-Fang4,Lin Che-Tong5,Burnouf Thierry67,Chen Li-You8,Kao Pan-Fu9,Chang Hung-Ming110ORCID

Affiliation:

1. Graduate Institute of Medical Sciences; College of Medicine; Taipei Medical University; Taipei Taiwan

2. School of Oral Hygiene; College of Oral Medicine; Taipei Medical University; Taipei Taiwan

3. School of Dentistry - Master and PhD Program; College of Oral Medicine; Taipei Medical University; Taipei Taiwan

4. School of Dental Technology; College of Oral Medicine; Taipei Medical University; Taipei Taiwan

5. Department of Dentistry; Taipei Medical University Hospital; Taipei Taiwan

6. Graduate Institute of Biomedical Materials and Tissue Engineering; College of Biomedical Engineering; Taipei Medical University; Taipei Taiwan

7. International PhD Program in Biomedical Engineering; College of Biomedical Engineering; Taipei Medical University; Taipei Taiwan

8. Department of Anatomy; School of Medicine; College of Medicine; Chung Shan Medical University; Taichung Taiwan

9. Department of Nuclear Medicine; School of Medicine; College of Medicine; Chung Shan Medical University; Taichung Taiwan

10. Department of Anatomy and Cell Biology; School of Medicine; College of Medicine; Taipei Medical University; Taipei Taiwan

Funder

Ministry of Science and Technology, Taiwan

Publisher

Wiley

Subject

Endocrinology

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