Granulomatous mastitis during pregnancy with sudden onset of gait difficulty and erythema nodosum: A case report and review of the literature

Author:

Miyahara Hideyuki1ORCID,Kurokawa Yusuke1,Muto Megumi1ORCID,Takao Yuko2,Iwanaga Erina3,Mihara Yutaro4,Fukushima Nao5,Yoshizato Toshiyuki1ORCID,Tsuda Naotake1

Affiliation:

1. Department of Obstetrics and Gynecology Kurume University School of Medicine Kurume Japan

2. Department of Surgery Kurume University School of Medicine Kurume Japan

3. Division of Respirology, Neurology and Rheumatology, Department of Medicine Kurume University School of Medicine Kurume Japan

4. Department of Pathology Kurume University School of Medicine Kurume Japan

5. Department of Clinical Laboratory Medicine Kurume University Hospital Kurume Japan

Abstract

AbstractGranulomatous mastitis (GM), a benign inflammatory disease of the breast, often mimics breast cancer on presentation. We present a case of GM during pregnancy manifesting as a breast mass, sudden onset of plantar pain, and erythema nodosum (EN). A 31‐year‐old pregnant Japanese woman, gravida 2, para 1, was referred to our hospital with severe plantar pain on both soles, causing difficulty walking. This pain worsened and EN appeared on both lower legs, followed by a left breast mass. Ultrasound findings suggested malignancy; however, aspiration biopsy confirmed GM. Her arthritis and EN resolved 2 days after commencing oral prednisolone and her walking improved. EN with/without arthritis is commonly associated with GM, especially during pregnancy. The described manifestations with a breast mass are suggestive of this diagnosis.

Publisher

Wiley

Reference15 articles.

1. Granulomatous mastitis with erythema nodosum during pregnancy: a case report;Mabuchi S;Cureus,2022

2. Granulomatous mastitis occurring during pregnancy: a case report;Yoshino R;Medicina (Kaunas),2023

3. Erythema nodosum and erythema induratum (nodular vasculitis): diagnosis and management;Gilchrist H;Dermatol Ther,2010

4. Patients with idiopathic granulomatous mastitis accompanied by erythema nodosum;Şener Bahçe Z;Int J Clin Pract,2021

5. What are the new findings with regard to the mysterious disease idiopathic granulomatous mastitis;Koksal H;Surg Today,2021

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