Proposal for a “phase II” multicenter trial model for preclinical new antiepilepsy therapy development-Reference-Cited by-同舟云学术

Proposal for a “phase II” multicenter trial model for preclinical new antiepilepsy therapy development

Published:2013-08 Issue: Volume:54 Page:70-74
ISSN:0013-9580
Container-title:Epilepsia
language:en
Short-container-title:Epilepsia

Author:

O'Brien Terence J.¹,Ben-Menachem Elinor²,Bertram Edward H.³,Collins Stephen D.⁴,Kokaia Merab⁵,Lerche Holger⁶,Klitgaard Henrik⁷,Staley Kevin J.⁸,Vaudano Elisabetta⁹,Walker Matthew C.¹⁰,Simonato Michele¹¹

Affiliation:

1. Departments of Medicine and Neurology; The Royal Melbourne Hospital; The University of Melbourne; Parkville; Victoria; Australia

2. Institute for Clinical Neurosciences; Sahlgrenska Academy; Göteborg; Sweden

3. Department of Neurology; University of Virginia Health System; Charlottesville; Virginia; U.S.A

4. NeuroTherapeutics Pharma; Chicago; Illinois; U.S.A

5. Experimental Epilepsy Group; Wallenberg Neuroscience Center; BMC; University Hospital; Lund; Sweden

6. Department of Neurology and Epileptology; Hertie-Institute for Clinical Brain Research; University Hospital Tübingen; Tübingen; Germany

7. UCB Pharma; Braine-l'Alleud; Belgium

8. Department of Neurology; Massachusetts General Hospital and Harvard Medical School; Boston; Massachusetts; U.S.A

9. Innovative Medicines Initiative (IMI); Brussels; Belgium

10. UCL Institute of Neurology; London; United Kingdom

11. Department of Medical Sciences, Section of Pharmacology; University of Ferrara, and National Institute of Neuroscience; Ferrara; Italy

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/epi.12300/fullpdf

Reference6 articles.

1. Identification of new epilepsy treatments: issues in preclinical methodology;Galanopoulou;Epilepsia,2012

2. Epilepsy therapy development: Technical and methodological issues in studies with animal models;Galanopoulou;Epilepsia,2013

3. Should preclinical studies be registered?;Kimmelman;Nat Biotechnol,2012

4. A call for transparent reporting to optimize the predictive value of preclinical research;Landis;Nature,2012

5. Believe it or not: how much can we rely on published data on potential drug targets?;Prinz;Nat Rev Drug Discov,2011

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Preventative treatment of tuberous sclerosis complex with sirolimus: Phase I safety and efficacy results;Annals of the Child Neurology Society;2024-04-22

2. Successful harmonization in EpiBioS4Rx biomarker study on post-traumatic epilepsy paves the way towards powered preclinical multicenter studies;Epilepsy Research;2024-01

3. Epilepsy phenotype and its reproducibility after lateral fluid percussion‐induced traumatic brain injury in rats: Multicenter EpiBioS4Rx study project 1;Epilepsia;2023-12-12

4. Disease-modifying effects of sodium selenate in a model of drug-resistant, temporal lobe epilepsy;eLife;2023-03-09

5. A systematic assessment of preclinical multilaboratory studies and a comparison to single laboratory studies;eLife;2023-03-09